Disable Self Heal in Adobe Reader 8
How to prevent Adobe Reader 8 from reinstalling its junk on every launch after you cleaned it up:
Open the file Adobe Reader.app/Contents/MacOS/SHInit.xml in a text editor or in Property List Editor;
Comment out or delete the following line:
<key>selfhealingfilename</key><string>RdrENU80SelfHeal.xml</string>Save the file;
Optional but highly recommended: show Adobe a sign of your triumph.